Fraen Corporation Srl started in 2004 to develop integrated optical solutions for fluorescence microscopy, consisting of a unique proprietary illumination system, which can be attached to many standard models of microscopes. This provided fluorescence capabilities with astonishing results on a wide range of specimens and fluorchromes.

What is special about FluoLED?

A high power solid-state (LED) source replace the mercury or xenon arc-lamps employed in traditional epifluorescence microscopy.

This approach provides significant increase of performance and light source lifetime, reduction of initial costs and operating costs, reduction of maintenance and heat production.

The module is designed to attach to a standard bright field microscope in any way. The fluorescence light source is used in transmission mode and will not void any warranties. Bright field microscopy is not affected since the halogen white light function remains intact, which means that transmitted light observation is possible without major changes in the optical configuration.

A fluorescent image of poor quality can lead to inaccurate clinical assumptions and this can result in incorrect diagnosis and improper treatment. Therefore optimized fluorescence microscopy is of major importance in the assessment of autoimmune diseases.

FluoLED was developed to provide performance and capability comparable to standard fluorescence microscopy equipment, but with serveral enhancements designed to make the technology accessible to more users, easier to operate and maintain, and significantly smaller.

There are four main aspects of FluoLED that allow it to meet the needs of the autoimmune laboratory, while reducing the complexity of operation

1. No complex alignment procedure of the light source is required. The LED cassette fits into the microscope adapter without use of any tool: this avoids the risk of poor fluorescence signals due to misalignment of the light source.
2. The FluoLED LED source reaches maximum efficiency immediately after turning the power on. There is no warm up time and no waiting period for re-starting, so the overall workflow is significantly increased.
3. FluoLED is cost-effective: consider how many arc lamps are used in 30,000 hours (the typical life time of a solid state source used in FluoLED).
4. Hg lamps can fail catastrophically. FluoLED avoids the risk of contaminating the laboratory with potentially harmful gases and saves expensive components of the microscope.

Fluorescence microscopy is a valuable tool for quality control in the modern food industry, where performance and ease of use are of major importance.