NOVA View uses computer algorithms to provide consistent results
NOVA View uses digital technology to create images of stained HEp-2 wells, and computer algorithms to measure the nuclear light intensity within individual cells.
- NOVA View measures pixel intensity and light distribution, in a manner similar to the three-dimensional histograms below
- NOVA View algorithms identify five of the most common ANA patterns: homogeneous, speckled, centromere, nucleolar and nuclear dot
- NOVA View displays images of mitotic cells to facilitate ANA pattern confirmation
NOVA View offers excellent agreement with manual HEp-2 results
Proprietary slides are used to calibrate NOVA View instruments to provide consistent light intensity and image quality.
1. NOVA Lite DAPI ANA Kit direction insert
- 120 samples were tested to determine the level of agreement between NOVA View and manual HEp-2 results1, 2
- This study confirms that results obtained by the operator reviewing NOVA View acquired images provide excellent agreement with reading performed on a manual IFA microscope
2. Data on file
NOVA View single well titer reduces the overall number of HEp-2 wells used
Example in a laboratory with an average volume of 100 ANA tests per day, a 20% positive rate, 5% of which are mixed patterns, performing 5 dilutions per well
- ANA screen: Both methods require the same number of wells for screening
- Titer: NOVA View SWT uses the light intensity from a single screening well to predict a titer, whereas
manual IFA requires additional wells to provide a similar result
In this example, NOVA View has the potential to reduce the total number of IFA wells by 48%.
- NOVA View SWT reduces the number of dilution wells by approximately 24,700 each year in this example
- NOVA View SWT improves turnaround time, lowers material costs and reduces technologist hands-on time
The Integrated Lab
The Integrated Lab
The Integrated Lab represents a new standard for improving workflow efficiencies in the autoimmunity laboratory. NOVA View is a key component in the Integrated Lab for automating IFA testing.
Inova Diagnostic instruments are connected together by QUANTA Link®, a data management software program that exchanges data with the laboratory information system. The instruments and software that make up the Integrated Lab encompass:
- QUANTA-Lyser®, a fully automated EIA/IFA processor
- NOVA View®, an automated digital IFA microscope
- BIO-FLASH®, a random access, continuous load chemiluminescent system
The Integrated Laboratory provides particular benefits for IFA testing:
- Significant reduction in hands-on time and improved workflow efficiencies
- Full traceability of patient samples from processing through reporting
- A paperless, transcription free laboratory operating environment
- Single point location for QC data including Levy Jennings trending
- Centralized data management system