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NOVA View®

NOVA View is the first automated digital IFA microscope to receive FDA clearance for detection of antinuclear antibodies.

  • NOVA View automatically acquires and presents digital images of HEp-2 cells for operator review and confirmation
  • NOVA View recognizes and displays mitotic cells and identifies five common ANA patterns
  • Single well titer prediction can reduce IFA workload and lower material costs
  • NOVA Lite® DAPI ANA Kit provides optimal clinical sensitivity and specificity, and excellent agreement with manual IFA
  • DAPI stain provides built-in control to visualize cells in a negative well
  • Calibration technique facilitates standardization

Step confidently into the future of digital IFA with NOVA View.
Image Analysis

NOVA View uses computer algorithms to provide consistent results

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NOVA View uses digital technology to create images of stained ANCA wells, and computer algorithms to measure the nuclear light intensity within individual cells.

  • NOVA View uses DAPI stain to identify the location of each cell and to differentiate between intranuclear and cytoplasmic staining.
  • A NOVA View operator can use DAPI images to confirm the presence of cells in negative samples.


  • NOVA View algorithms identify two primary ANCA ethanol and formalin patterns: cytoplasmic and perinuclear.

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Agreement with Manual IFA

NOVA View offers excellent agreement with manual HEp-2 results

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Proprietary slides are used to calibrate NOVA View instruments to provide consistent light intensity and image quality.

  • 120 samples were tested to determine the level of agreement between NOVA View and manual HEp-2 results1, 2
  • This study confirms that results obtained by the operator reviewing NOVA View acquired images provide excellent agreement with reading performed on a manual IFA microscope


1. NOVA Lite DAPI ANA Kit direction insert
2. Data on file


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Proprietary slides are used to calibrate NOVA View instruments to provide consistent light intensity and image quality.

  • 653 samples were tested to determine the level of agreement between NOVA View and manual ANCA ethanol and formalin results1
  • This study confirms that results obtained by the operator reviewing NOVA View acquired images provide excellent agreement with reading performed on a manual IFA microscope



1. NOVA Lite DAPI ANA Kit direction insert


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Economic Benefits

NOVA View single well titer reduces the overall number of HEp-2 wells used

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Example in a laboratory with an average volume of 100 ANA tests per day, a 20% positive rate, 5% of which are mixed patterns, performing 5 dilutions per well

  • ANA screen: Both methods require the same number of wells for screening
  • Titer: NOVA View SWT uses the light intensity from a single screening well to predict a titer, whereas manual IFA requires additional wells to provide a similar result




In this example, NOVA View has the potential to reduce the total number of IFA wells by 48%.

  • NOVA View SWT reduces the number of dilution wells by approximately 24,700 each year in this example
  • NOVA View SWT improves turnaround time, lowers material costs and reduces technologist hands-on time











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Example in a laboratory with an average volume of 100 ANCA ethanol tests per day, a 10% positive rate, performing 5 dilutions per well

  • ANA screen: Both methods require the same number of wells for screening
  • Titer: NOVA View SWT uses the light intensity from a single screening well to predict a titer, whereas manual IFA requires additional wells to provide a similar result




In this example, NOVA View has the potential to reduce the total number of IFA wells by 33%.

  • NOVA View SWT reduces the number of dilution wells by approximately 13,000 each year in this example
  • NOVA View SWT improves turnaround time, lowers material costs and reduces technologist hands-on time











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The Integrated Lab

The Integrated Lab

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To learn more about NOVA View and it’s capabilities, download the complete brochure. Download Brochure PDF >